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Cryptococcal antigen latex agglutination test

Specimen type

Cryptococcal antigen latex agglutination test

 

 

Optimal time of specimen collection

Collection is not time dependent. On suspicion of cryptococcosis

Correct specimen type and method of collection

CSF by lumbar puncture, serum, urine and BAL

Quantity and number of specimens

Minimum 500 ml CSF. Other specimen types variable. With appropriate controls, a positive test is indicative of infection. Perform repeat lumbar puncture after 2 weeks of treatment. Repeated testing can be used to monitor response to treatment, monitor for duration of treatment course, especially in HIV-positive patients.

Laboratory analysis

Latex agglutination test for cryptococcal antigen

Transport

As per Microbiology guidelines

Indicative cost per sample

£31.60

 

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